MALLINCKRODT MEDICAL INC -- HIPPURAN I 131 INJECTION  -- 6505-00F035477
<pre>=====================  Product Identification  =====================

Product ID:HIPPURAN I 131 INJECTION
MSDS Date:01/01/1995
FSC:6505
NIIN:00F035477
=== Responsible Party ===
Company Name:MALLINCKRODT MEDICAL INC
Address:2703 WAGNER PLACE
City:MARYLAND HEIGHTS
State:MO
ZIP:63043-3421
Country:US
Info Phone Num:314-770-7800/314-895-2000
Emergency Phone Num:314-770-7800
CAGE:FO650
=== Contractor Identification ===
Company Name:MALLINCKRODT DIAGNOSTICS
Address:2703 WAGNER PLACE
Box:City:MARYLAND HEIGHTS
State:MO
ZIP:63043-3421
Country:US
Phone:314-344-3800
CAGE:2A916
Company Name:MALLINCKRODT MEDICAL INC
Address:2703 WAGNER PLACE
City:MARYLAND HEIGHTS
State:MO
ZIP:63043-3421
Country:US
Phone:314-770-7800/314-895-2000
CAGE:FO650

=============  Composition/Information on Ingredients  =============

Ingred Name:HIPPURAN I 131
CAS:881-17-4
Fraction by Wt: <1%

Ingred Name:DISODIUM EDETATE; ACETIC ACID, (ETHYLENEDINITRILO)TETRA-,
    DISODIUM SALT; EDTA DISODIUM
CAS:139-33-3
RTECS #:AH4375000
Fraction by Wt: 0.005%

Ingred Name:SODIUM CITRATE, TRISODIUM SALT, CITRIC ACID
CAS:68-04-2
RTECS #:GE8300000
Fraction by Wt: 0.02%

Ingred Name:BENZOIC ACID, 4-HYDROXY-, PROPYL ESTER, PROPYLPARABEN
CAS:94-13-3
RTECS #:DH2800000
Fraction by Wt: 0.03%

Ingred Name:METHYL PARAHYDROXYBENZOATE, METHYLPARABEN
CAS:99-76-3
RTECS #:DH2450000
Fraction by Wt: 0.1%

Ingred Name:1,2-PROPANEDIOL (PROPYLENE GLYCOL)
CAS:57-55-6
RTECS #:TY2000000
Fraction by Wt: 37.5%

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:NO	Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:RADIOACTIVE MATERIAL. SKIN:
    IRRITATION. EYES: MECHANICAL IRRITATION. INGESTION: ASYMPTOMATIC
    PHYSIOLOGICAL UPTAKE BY THYROID GLAND/OTHER TISSUES. UPTAKE OF
    I-131 BY THYROID GLAND CAN RESULT IN SLIGHT  TO TOTAL THYROID
    DYSFUNCTION. CHRONIC RADIATION EXPOSURE MAY CAUSE CANCER, LEUKEMIA,
    GENETIC & TERATOGENIC EFFECTS.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION.

=======================  First Aid Measures  =======================

First Aid:NOTIFY RADIATION SAFETY PERSONNEL IMMEDIATELY. INHALATION:
    ASSESS/DOCUMENT AMOUNT OF MATERIAL. INGESTION: ASSESS/DOCUMENT
    AMOUNT OF I-131 IN THYROID GLAND. THYROID BLOCKING AGENT MAY BE
    WARRANTED. SKI N: WASH AFFECTED AREA THOROUGHLY W/SOAP& WATER.
    ALWAYS BLOT DRY. DON'T ABRADE SKIN. EYES: FLUSH W/WATER FOR 15
    MINS/UNTIL NO MORE RADIOACTIVITY CAN BE REMOVED. OBTAIN MEDICAL
    ATTENTION IN ALL CASES.

=====================  Fire Fighting Measures  =====================

Flash Point:NON-FLAMMABLE
Extinguishing Media:USE MEDIA APPROPRIATE FOR SURROUNDING FIRE.
Fire Fighting Procedures:WEAR A NIOSH APPROVED SELF-CONTAINED BREATHING
    APPARATUS W/FULL FACEPIECE OPERATED IN PRESSURE DEMAND/OTHER
    POSITIVE PRESSURE MODE & FULL PROTECTIVE CLOTHING.

==================  Accidental Release Measures  ==================

Spill Release Procedures:IF PRODUCT IS RECEIVED IN A LEAKING
    CONDITION/ANY LOSS/RELEASE OF RADIOACTIVE CONTENTS OCCURS, NOTIFY
    YOUR RADIATION SAFETY DEPARTMENT & MALLINCKRODT @ 314-770-7800.
    (SEE SUPP)

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE BETWEEN 59-86F. KEEP HANDLING
    TIME TO MINIMUM & USE APPROPRIATE SHIELDING. USE SYRINGE SHIELDS &
    TONGS WHEN HANDLING.
Other Precautions:STORAGE & DISPOSAL OF PRODUCT SHOULD BE CONTROLLED
    IAW/APPROPRIATE REGULATIONS OF FEDERAL/STATE GOVERNMENT AGENCY
    AUTHORIZED TO LICENSE USE OF THIS RADIONUCLIDE. DON'T SMOKE,
    EAT/DRINK WHERE RADIOACTI VE MATERIALS ARE HANDLED/STORED.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NOT EXPECTED TO REQUIRE USE OF PERSONAL
    RESPIRATOR.
Ventilation:PROPERLY SEALED CONTAINERS AREN'T EXPECTED TO REQUIRE ANY
    SPECIAL VENTILATION.
Protective Gloves:DISPOSABLE PLASTIC, LATEX, RUBBER
Eye Protection:SAFETY GLASSES.
Other Protective Equipment:DISPOSABLE LABCOAT
Supplemental Safety and Health
SPILL PROCEDURES: ALL CLEANUP OPERATIONS SHOULD BE PERFORMED
    IAW/STANDARD OPERATING PROCEDURES, NRC/OTHER APPLICABLE FEDERAL,
    STATE & LOCAL REGULATIONS. WASTE DISPOSAL: WASTE HIPPURAN I 131 IS
    NON-HAZ ARDOUS IF NOT RADIOACTIVE/A BIOHAZARD. RADIOACTIVE MATERIAL
    UN 2982.

==================  Physical/Chemical Properties  ==================

Boiling Pt:B.P. Text:212F
Melt/Freeze Pt:M.P/F.P Text:32F
Solubility in Water:COMPLETE
Appearance and Odor:CLEAR, COLORLESS LIQUID IN A 10 ML GLASS VIAL W/NO
    ODOR.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:HEATED TO DECOMPOSITION: RADIOACTIVE
    FUMES CONTAINING I-131.

====================  Disposal Considerations  ====================

Waste Disposal Methods:HIPPURAN I 131 IS RADIOACTIVE WASTE UNTIL
    ACTIVITY HAS DECAYED TO NONDETECTABLE LEVELS. RADIOACTIVE WASTE
    MUST BE HANDLED IAW/NRC, FEDERAL, STATE & LOCAL REGULATIONS.
    MEDICAL WASTE, BLOOD, BLOOD PRODU CTS/SHARPS MUST BE HANDLED AS
    BIOHAZARD. (SUPP)

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